TY - JOUR
T1 - Influence of copper status on the accumulation of toxic and essential metals in cattle
AU - Blanco Penedo, Maria Isabel
AU - Cruz, J. M.
AU - Lopez-Alonso, M.
AU - Miranda, M.
AU - Castillo, C.
AU - Hernandez, J.
AU - Benedito, J. L.
PY - 2006
Y1 - 2006
N2 - The aim of the present study was to assess whether the use of pig slurry and associated copper accumulation in calves grazing pastures fertilized with pig slurry from the Deza region in NW Spain has a significant influence on toxic metal and essential metal levels, and to investigate whether copper accumulation is correlated with the levels of these other metals. Correlations between copper, toxic metals (cadmium, lead) and essential metals (molybdenum, iron, zinc, selenium, manganese and cobalt) concentrations were evaluated in liver and kidney of 195 calves from the region of Deza. Metal concentrations were determined by ICP-OES and correlations between pairs of elements by Pearson correlation analysis. There was a strongly significant positive association between copper and lead in the liver. Considering the trace metals, copper in the liver showed significant positive correlations with cobalt in both liver and kidney, and with molybdenum in the liver. In addition, significant correlations were observed between copper and most essential metals in kidney. These associations are similar to those found in different animal species experimentally dosed with copper and other metals, as well as in cattle exposed to normal copper concentrations. (c) 2006 Elsevier Ltd. All rights reserved.
AB - The aim of the present study was to assess whether the use of pig slurry and associated copper accumulation in calves grazing pastures fertilized with pig slurry from the Deza region in NW Spain has a significant influence on toxic metal and essential metal levels, and to investigate whether copper accumulation is correlated with the levels of these other metals. Correlations between copper, toxic metals (cadmium, lead) and essential metals (molybdenum, iron, zinc, selenium, manganese and cobalt) concentrations were evaluated in liver and kidney of 195 calves from the region of Deza. Metal concentrations were determined by ICP-OES and correlations between pairs of elements by Pearson correlation analysis. There was a strongly significant positive association between copper and lead in the liver. Considering the trace metals, copper in the liver showed significant positive correlations with cobalt in both liver and kidney, and with molybdenum in the liver. In addition, significant correlations were observed between copper and most essential metals in kidney. These associations are similar to those found in different animal species experimentally dosed with copper and other metals, as well as in cattle exposed to normal copper concentrations. (c) 2006 Elsevier Ltd. All rights reserved.
KW - copper accumulation
KW - cattle
KW - metal interactions
KW - toxic and essential elements
KW - copper accumulation
KW - cattle
KW - metal interactions
KW - toxic and essential elements
UR - https://res.slu.se/id/publ/101324
U2 - 10.1016/j.envint.2006.05.012
DO - 10.1016/j.envint.2006.05.012
M3 - Journal article
SN - 0160-4120
VL - 32
SP - 901
EP - 906
JO - Environment International
JF - Environment International
IS - 7
ER -