CYP 3A in horse intestines

Eva Tyden; Lena Olsén; Pia Larsson; Hans Tjälve; Jonas Tallkvist

CYP 3A in horse intestines

Eva Tyden
, Lena Olsén
, Pia Larsson
, Hans Tjälve
, Jonas Tallkvist

Publikation: Bidrag till tidskrift › Artikel i vetenskaplig tidskrift › Peer review

Sammanfattning

The intestinal enterocytes provide the initial site for cytochrome P450 (CYP)-mediated metabolism of orally absorbed xenobiotics. In man and some animal species, the CYP 3A subfamily is highly expressed in the intestines and considered to be important in the first-pass metabolism of drugs and other xenobiotics. Aim: to investigate the mRNA expression, immunohistochemical localization and catalytic activity of CYP 3A in the intestines of horse

Originalspråk	Engelska
Sidor (från-till)	112-119
Antal sidor	8
Tidskrift	Toxicology and Applied Pharmacology
Volym	201
Status	Publicerad - 2004

Nyckelord

CYP 3A
horse

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title = "CYP 3A in horse intestines",

abstract = "The intestinal enterocytes provide the initial site for cytochrome P450 (CYP)-mediated metabolism of orally absorbed xenobiotics. In man and some animal species, the CYP 3A subfamily is highly expressed in the intestines and considered to be important in the first-pass metabolism of drugs and other xenobiotics. Aim: to investigate the mRNA expression, immunohistochemical localization and catalytic activity of CYP 3A in the intestines of horse",

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author = "Eva Tyden and Lena Ols{\'e}n and Pia Larsson and Hans Tj{\"a}lve and Jonas Tallkvist",

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journal = "Toxicology and Applied Pharmacology",

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T1 - CYP 3A in horse intestines

AU - Tyden, Eva

AU - Olsén, Lena

AU - Larsson, Pia

AU - Tjälve, Hans

AU - Tallkvist, Jonas

PY - 2004

Y1 - 2004

N2 - The intestinal enterocytes provide the initial site for cytochrome P450 (CYP)-mediated metabolism of orally absorbed xenobiotics. In man and some animal species, the CYP 3A subfamily is highly expressed in the intestines and considered to be important in the first-pass metabolism of drugs and other xenobiotics. Aim: to investigate the mRNA expression, immunohistochemical localization and catalytic activity of CYP 3A in the intestines of horse

AB - The intestinal enterocytes provide the initial site for cytochrome P450 (CYP)-mediated metabolism of orally absorbed xenobiotics. In man and some animal species, the CYP 3A subfamily is highly expressed in the intestines and considered to be important in the first-pass metabolism of drugs and other xenobiotics. Aim: to investigate the mRNA expression, immunohistochemical localization and catalytic activity of CYP 3A in the intestines of horse

KW - CYP 3A

KW - horse

KW - CYP 3A

KW - horse

UR - https://res.slu.se/id/publ/4570

M3 - Journal article

SN - 0041-008X

VL - 201

SP - 112

EP - 119

JO - Toxicology and Applied Pharmacology

JF - Toxicology and Applied Pharmacology

ER -