Correspondence on Lovell et al.: identification of chicken genes previously assumed to be evolutionarily lost

Susanne Bornelöv; Eyal Seroussi; Sara Yosefi; Ken Pendavis; Shane C. Burgess; Manfred Grabherr; Miriam Friedman-Einat; Leif Andersson

doi:10.1186/s13059-017-1231-1

Correspondence on Lovell et al.: identification of chicken genes previously assumed to be evolutionarily lost

Susanne Bornelöv
, Eyal Seroussi
, Sara Yosefi
, Ken Pendavis
, Shane C. Burgess
, Manfred Grabherr
, Miriam Friedman-Einat
, Leif Andersson

Publikation: Bidrag till tidskrift › Artikel i vetenskaplig tidskrift › Peer review

Sammanfattning

Through RNA-Seq analyses, we identified 137 genes that are missing in chicken, including the long-sought-after nephrin and tumor necrosis factor genes. These genes tended to cluster in GC-rich regions that have poor coverage in genome sequence databases. Hence, the occurrence of syntenic groups of vertebrate genes that have not been observed in Aves does not prove the evolutionary loss of such genes.

Originalspråk	Engelska
Artikelnummer	112
Antal sidor	4
Tidskrift	Genome Biology
Volym	18
DOI	https://doi.org/10.1186/s13059-017-1231-1
Status	Publicerad - 2017

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10.1186/s13059-017-1231-1

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title = "Correspondence on Lovell et al.: identification of chicken genes previously assumed to be evolutionarily lost",

abstract = "Through RNA-Seq analyses, we identified 137 genes that are missing in chicken, including the long-sought-after nephrin and tumor necrosis factor genes. These genes tended to cluster in GC-rich regions that have poor coverage in genome sequence databases. Hence, the occurrence of syntenic groups of vertebrate genes that have not been observed in Aves does not prove the evolutionary loss of such genes.",

author = "Susanne Bornel{\"o}v and Eyal Seroussi and Sara Yosefi and Ken Pendavis and Burgess, \{Shane C.\} and Manfred Grabherr and Miriam Friedman-Einat and Leif Andersson",

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doi = "10.1186/s13059-017-1231-1",

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AU - Bornelöv, Susanne

AU - Seroussi, Eyal

AU - Yosefi, Sara

AU - Pendavis, Ken

AU - Burgess, Shane C.

AU - Grabherr, Manfred

AU - Friedman-Einat, Miriam

AU - Andersson, Leif

PY - 2017

Y1 - 2017

N2 - Through RNA-Seq analyses, we identified 137 genes that are missing in chicken, including the long-sought-after nephrin and tumor necrosis factor genes. These genes tended to cluster in GC-rich regions that have poor coverage in genome sequence databases. Hence, the occurrence of syntenic groups of vertebrate genes that have not been observed in Aves does not prove the evolutionary loss of such genes.

AB - Through RNA-Seq analyses, we identified 137 genes that are missing in chicken, including the long-sought-after nephrin and tumor necrosis factor genes. These genes tended to cluster in GC-rich regions that have poor coverage in genome sequence databases. Hence, the occurrence of syntenic groups of vertebrate genes that have not been observed in Aves does not prove the evolutionary loss of such genes.

UR - https://res.slu.se/id/publ/91110

U2 - 10.1186/s13059-017-1231-1

DO - 10.1186/s13059-017-1231-1

M3 - Journal article

C2 - 28615067

SN - 1474-7596

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JO - Genome Biology

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