Antifungal 3-hydroxy fatty acids from Lactobacillus plantarum MiLAB 14

Jörgen Sjögren; Jesper Magnusson; Anders Broberg; Johan Schnürer; Lennart Kenne

doi:10.1128/AEM.69.12.7554-7557.2003

Antifungal 3-hydroxy fatty acids from Lactobacillus plantarum MiLAB 14

Jörgen Sjögren
, Jesper Magnusson
, Anders Broberg
, Johan Schnürer
, Lennart Kenne

Publikation: Bidrag till tidskrift › Artikel i vetenskaplig tidskrift › Peer review

Sammanfattning

We report the identification and chemical characterization of four antifungall substances, 3-(R)-hydroxydecanoic acid, 3-hydroxy-5-cis-dodecenoic acid, 3-(R)-hydroxydodecanoic acid and 3-(R)-hydroxytetradecanoic acid, from Lactobacillus plantarum MiLAB 14. The concentrations of the 3-hydroxy fatty acids in the supernatant followed the bacterial growth. Racemic mixtures of the saturated 3-hydroxy fatty acids showed antifungal activity against different molds and yeasts with MICs between 10 and 100 mug ml(-1).

Originalspråk	Engelska
Sidor (från-till)	7554-7557
Antal sidor	4
Tidskrift	Applied and Environmental Microbiology
Volym	69
Nummer	12
DOI	https://doi.org/10.1128/AEM.69.12.7554-7557.2003
Status	Publicerad - 2003

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10.1128/AEM.69.12.7554-7557.2003

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title = "Antifungal 3-hydroxy fatty acids from Lactobacillus plantarum MiLAB 14",

abstract = "We report the identification and chemical characterization of four antifungall substances, 3-(R)-hydroxydecanoic acid, 3-hydroxy-5-cis-dodecenoic acid, 3-(R)-hydroxydodecanoic acid and 3-(R)-hydroxytetradecanoic acid, from Lactobacillus plantarum MiLAB 14. The concentrations of the 3-hydroxy fatty acids in the supernatant followed the bacterial growth. Racemic mixtures of the saturated 3-hydroxy fatty acids showed antifungal activity against different molds and yeasts with MICs between 10 and 100 mug ml(-1).",

author = "J{\"o}rgen Sj{\"o}gren and Jesper Magnusson and Anders Broberg and Johan Schn{\"u}rer and Lennart Kenne",

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T1 - Antifungal 3-hydroxy fatty acids from Lactobacillus plantarum MiLAB 14

AU - Sjögren, Jörgen

AU - Magnusson, Jesper

AU - Broberg, Anders

AU - Schnürer, Johan

AU - Kenne, Lennart

PY - 2003

Y1 - 2003

N2 - We report the identification and chemical characterization of four antifungall substances, 3-(R)-hydroxydecanoic acid, 3-hydroxy-5-cis-dodecenoic acid, 3-(R)-hydroxydodecanoic acid and 3-(R)-hydroxytetradecanoic acid, from Lactobacillus plantarum MiLAB 14. The concentrations of the 3-hydroxy fatty acids in the supernatant followed the bacterial growth. Racemic mixtures of the saturated 3-hydroxy fatty acids showed antifungal activity against different molds and yeasts with MICs between 10 and 100 mug ml(-1).

AB - We report the identification and chemical characterization of four antifungall substances, 3-(R)-hydroxydecanoic acid, 3-hydroxy-5-cis-dodecenoic acid, 3-(R)-hydroxydodecanoic acid and 3-(R)-hydroxytetradecanoic acid, from Lactobacillus plantarum MiLAB 14. The concentrations of the 3-hydroxy fatty acids in the supernatant followed the bacterial growth. Racemic mixtures of the saturated 3-hydroxy fatty acids showed antifungal activity against different molds and yeasts with MICs between 10 and 100 mug ml(-1).

UR - https://res.slu.se/id/publ/611

U2 - 10.1128/AEM.69.12.7554-7557.2003

DO - 10.1128/AEM.69.12.7554-7557.2003

M3 - Journal article

C2 - 14660414

SN - 0099-2240

VL - 69

SP - 7554

EP - 7557

JO - Applied and Environmental Microbiology

JF - Applied and Environmental Microbiology

IS - 12

ER -