The Longitudinal Outcome Of Canine (K9) myxomatous mitral valve disease (LOOK- Mitral registry): Baseline characteristics

Introduction: The Longitudinal Outcome Of Canine (K9) myxomatous mitral valve disease (MMVD) registry (LOOK-Mitral registry) was established to de-scribe the natural history and predictors of outcome in dogs affected by MMVD. This study was intended to describe the baseline characteristics of dogs in the LOOK-mitral registry. Animals: Dogs with echocardiographic evidence of MMVD were prospectively enrolled by thirteen referral centers. Results: A total of 6102 dogs with MMVD were included. The median age was 10 years (1e19 years), and mixed breed was the most common breed (n 1/4 1,360, 22%). Concomitant diseases were reported in 2459 dogs with chronic respiratory diseases occurring most frequently (14%), followed by the presence of azotemia (6%) and orthopedic diseases (5%). Regarding disease severity, 65% of dogs were in ACVIM Stage-B1, 15% in Stage-B2, and 20% in Stage-C. Dogs in Stage-B1 were younger (p1.26). Conclusions: This study contributes to a better understanding of the clinical characteristics of dogs affected by MMVD and provides new findings that may be of clinical relevance. 2021 Elsevier B.V. All rights reserved.