The effects of pulse-delivered inhaled nitric oxide on arterial oxygenation, ventilation-perfusion distribution and plasma endothelin-1 concentration in laterally recumbent isoflurane-anaesthetized horses

Tamara Grubb; Tamara Grubb; Jan Frendin; Anna Edner; Pia Funkquist; Göran Hedenstierna; Görel Nyman

doi:10.1111/vaa.12037

The effects of pulse-delivered inhaled nitric oxide on arterial oxygenation, ventilation-perfusion distribution and plasma endothelin-1 concentration in laterally recumbent isoflurane-anaesthetized horses

Tamara Grubb
, Tamara Grubb
, Jan Frendin
, Anna Edner
, Pia Funkquist
, Göran Hedenstierna
, Görel Nyman

Publication: Contribution to journal › Journal article › peer-review

Abstract

Conclusions and Clinical Relevance PiNO delivered in the initial portion of the inspiration effectively relieves hypoxaemia in anaesthetized horses by improving ((V) over dot(A)/(Q) over dot) matching and decreasing ((Q) over dots/(Q) over dott) without affecting ET-1.

Original language	English
Pages (from-to)	E19-E30
Journal	Veterinary Anaesthesia and Analgesia
Volume	40
Issue number	6
DOIs	https://doi.org/10.1111/vaa.12037
Publication status	Published - 2013

Keywords

anaesthesia
endothelin-1
gas exchange
horse
hypoxaemia
MIGET
nitric oxide
(Q) over dots/(Q) over dott
shunt
(V) over dot(A)/(Q) over dot

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10.1111/vaa.12037

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Grubb, T., Grubb, T., Frendin, J., Edner, A., Funkquist, P., Hedenstierna, G., & Nyman, G. (2013). The effects of pulse-delivered inhaled nitric oxide on arterial oxygenation, ventilation-perfusion distribution and plasma endothelin-1 concentration in laterally recumbent isoflurane-anaesthetized horses. Veterinary Anaesthesia and Analgesia, 40(6), E19-E30. https://doi.org/10.1111/vaa.12037

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title = "The effects of pulse-delivered inhaled nitric oxide on arterial oxygenation, ventilation-perfusion distribution and plasma endothelin-1 concentration in laterally recumbent isoflurane-anaesthetized horses",

abstract = "Conclusions and Clinical Relevance PiNO delivered in the initial portion of the inspiration effectively relieves hypoxaemia in anaesthetized horses by improving ((V) over dot(A)/(Q) over dot) matching and decreasing ((Q) over dots/(Q) over dott) without affecting ET-1.",

keywords = "anaesthesia, endothelin-1, gas exchange, horse, hypoxaemia, MIGET, nitric oxide, (Q) over dots/(Q) over dott, shunt, (V) over dot(A)/(Q) over dot, anaesthesia, endothelin-1, gas exchange, horse, hypoxaemia, MIGET, nitric oxide, (Q) over dots/(Q) over dott, shunt, (V) over dot(A)/(Q) over dot",

author = "Tamara Grubb and Tamara Grubb and Jan Frendin and Anna Edner and Pia Funkquist and G{\"o}ran Hedenstierna and G{\"o}rel Nyman",

year = "2013",

doi = "10.1111/vaa.12037",

language = "English",

volume = "40",

pages = "E19--E30",

journal = "Veterinary Anaesthesia and Analgesia",

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Grubb, T, Grubb, T, Frendin, J, Edner, A, Funkquist, P, Hedenstierna, G & Nyman, G 2013, 'The effects of pulse-delivered inhaled nitric oxide on arterial oxygenation, ventilation-perfusion distribution and plasma endothelin-1 concentration in laterally recumbent isoflurane-anaesthetized horses', Veterinary Anaesthesia and Analgesia, vol. 40, no. 6, pp. E19-E30. https://doi.org/10.1111/vaa.12037

The effects of pulse-delivered inhaled nitric oxide on arterial oxygenation, ventilation-perfusion distribution and plasma endothelin-1 concentration in laterally recumbent isoflurane-anaesthetized horses. / Grubb, Tamara; Grubb, Tamara; Frendin, Jan et al.
In: Veterinary Anaesthesia and Analgesia, Vol. 40, No. 6, 2013, p. E19-E30.

Publication: Contribution to journal › Journal article › peer-review

TY - JOUR

T1 - The effects of pulse-delivered inhaled nitric oxide on arterial oxygenation, ventilation-perfusion distribution and plasma endothelin-1 concentration in laterally recumbent isoflurane-anaesthetized horses

AU - Grubb, Tamara

AU - Frendin, Jan

AU - Edner, Anna

AU - Funkquist, Pia

AU - Hedenstierna, Göran

AU - Nyman, Görel

PY - 2013

Y1 - 2013

N2 - Conclusions and Clinical Relevance PiNO delivered in the initial portion of the inspiration effectively relieves hypoxaemia in anaesthetized horses by improving ((V) over dot(A)/(Q) over dot) matching and decreasing ((Q) over dots/(Q) over dott) without affecting ET-1.

AB - Conclusions and Clinical Relevance PiNO delivered in the initial portion of the inspiration effectively relieves hypoxaemia in anaesthetized horses by improving ((V) over dot(A)/(Q) over dot) matching and decreasing ((Q) over dots/(Q) over dott) without affecting ET-1.

KW - anaesthesia

KW - endothelin-1

KW - gas exchange

KW - horse

KW - hypoxaemia

KW - MIGET

KW - nitric oxide

KW - (Q) over dots/(Q) over dott

KW - shunt

KW - (V) over dot(A)/(Q) over dot

KW - anaesthesia

KW - endothelin-1

KW - gas exchange

KW - horse

KW - hypoxaemia

KW - MIGET

KW - nitric oxide

KW - (Q) over dots/(Q) over dott

KW - shunt

KW - (V) over dot(A)/(Q) over dot

UR - https://res.slu.se/id/publ/56198

U2 - 10.1111/vaa.12037

DO - 10.1111/vaa.12037

M3 - Journal article

C2 - 23601237

SN - 1467-2987

VL - 40

SP - E19-E30

JO - Veterinary Anaesthesia and Analgesia

JF - Veterinary Anaesthesia and Analgesia

IS - 6

ER -

The effects of pulse-delivered inhaled nitric oxide on arterial oxygenation, ventilation-perfusion distribution and plasma endothelin-1 concentration in laterally recumbent isoflurane-anaesthetized horses

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Keywords

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