Support of Concept That Migrating Progenitor Cells From Stem Cell Niches Contribute to Normal Regeneration of the Adult Mammal Intervertebral Disc A Descriptive Study in the New Zealand White Rabbit

Helena Barreto Henriksson; Emilia Svala; Eva Skiöldebrand; Anders Lindahl; Helena Brisby

doi:10.1097/BRS.0b013e318231c2f7

Support of Concept That Migrating Progenitor Cells From Stem Cell Niches Contribute to Normal Regeneration of the Adult Mammal Intervertebral Disc A Descriptive Study in the New Zealand White Rabbit

Helena Barreto Henriksson
, Emilia Svala
, Eva Skiöldebrand
, Anders Lindahl
, Helena Brisby

Publication: Contribution to journal › Journal article › peer-review

Abstract

Conclusion. The results suggest a cellular MR from the IVD stem cell niche toward the annulus fibrosus and the inner parts of the IVD. These findings may be of importance for understanding IVD regenerative mechanisms and for future development of biological treatment strategies.

Original language	English
Pages (from-to)	722-732
Number of pages	11
Journal	Spine
Volume	37
Issue number	9
DOIs	https://doi.org/10.1097/BRS.0b013e318231c2f7
Publication status	Published - 2012

Keywords

disc regeneration
cell migration
stem cell niches
intervertebral disc
in vivo labeling
BrdU
GDF5

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10.1097/BRS.0b013e318231c2f7

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title = "Support of Concept That Migrating Progenitor Cells From Stem Cell Niches Contribute to Normal Regeneration of the Adult Mammal Intervertebral Disc A Descriptive Study in the New Zealand White Rabbit",

abstract = "Conclusion. The results suggest a cellular MR from the IVD stem cell niche toward the annulus fibrosus and the inner parts of the IVD. These findings may be of importance for understanding IVD regenerative mechanisms and for future development of biological treatment strategies.",

keywords = "disc regeneration, cell migration, stem cell niches, intervertebral disc, in vivo labeling, BrdU, GDF5, disc regeneration, cell migration, stem cell niches, intervertebral disc, in vivo labeling, BrdU, GDF5",

author = "Henriksson, \{Helena Barreto\} and Emilia Svala and Eva Ski{\"o}ldebrand and Anders Lindahl and Helena Brisby",

year = "2012",

doi = "10.1097/BRS.0b013e318231c2f7",

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volume = "37",

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journal = "Spine",

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Support of Concept That Migrating Progenitor Cells From Stem Cell Niches Contribute to Normal Regeneration of the Adult Mammal Intervertebral Disc A Descriptive Study in the New Zealand White Rabbit. / Henriksson, Helena Barreto; Svala, Emilia; Skiöldebrand, Eva et al.
In: Spine, Vol. 37, No. 9, 2012, p. 722-732.

Publication: Contribution to journal › Journal article › peer-review

TY - JOUR

T1 - Support of Concept That Migrating Progenitor Cells From Stem Cell Niches Contribute to Normal Regeneration of the Adult Mammal Intervertebral Disc A Descriptive Study in the New Zealand White Rabbit

AU - Henriksson, Helena Barreto

AU - Svala, Emilia

AU - Skiöldebrand, Eva

AU - Lindahl, Anders

AU - Brisby, Helena

PY - 2012

Y1 - 2012

N2 - Conclusion. The results suggest a cellular MR from the IVD stem cell niche toward the annulus fibrosus and the inner parts of the IVD. These findings may be of importance for understanding IVD regenerative mechanisms and for future development of biological treatment strategies.

AB - Conclusion. The results suggest a cellular MR from the IVD stem cell niche toward the annulus fibrosus and the inner parts of the IVD. These findings may be of importance for understanding IVD regenerative mechanisms and for future development of biological treatment strategies.

KW - disc regeneration

KW - cell migration

KW - stem cell niches

KW - intervertebral disc

KW - in vivo labeling

KW - BrdU

KW - GDF5

KW - disc regeneration

KW - cell migration

KW - stem cell niches

KW - intervertebral disc

KW - in vivo labeling

KW - BrdU

KW - GDF5

UR - https://res.slu.se/id/publ/45616

U2 - 10.1097/BRS.0b013e318231c2f7

DO - 10.1097/BRS.0b013e318231c2f7

M3 - Journal article

C2 - 21897341

SN - 0362-2436

VL - 37

SP - 722

EP - 732

JO - Spine

JF - Spine

IS - 9

ER -

Support of Concept That Migrating Progenitor Cells From Stem Cell Niches Contribute to Normal Regeneration of the Adult Mammal Intervertebral Disc A Descriptive Study in the New Zealand White Rabbit

Abstract

Keywords

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