TY - JOUR
T1 - Normal values for calprotectin in stool samples of infants from the population-based longitudinal born into life study
AU - Peura, Sari
AU - Fall, Tove
AU - Almqvist, Catarina
AU - Andolf, Ellika
AU - Hedman, Anna
AU - Pershagen, Göran
AU - Helmersson-Karlqvist, Johanna
AU - Larsson, Anders
PY - 2018
Y1 - 2018
N2 - Faecal calprotectin is a protein used as a diagnostic marker for inflammatory bowel diseases. We determined upper limits for normal calprotectin values for neonatal, 6, 12 and 24months old children using a turbidimetric immunoassay in a cohort of Swedish children. The advantage of the method is that opposite to previously used enzyme-linked immunosorbent assay (ELISA) method, it enables measuring single samples, and thus, shortens the analysis time significantly. There were 72 samples (41.7% female) collected neonatally, 63 samples (34.9% female) at 6months, 60 samples (40.0% female) at 12months and 51 samples (43.1% female) at 24months. The upper limits for normal values were 233, 615, 136 and 57 mu g mg(-1) for infants aged 0, 6, 12 and 24months, respectively.
AB - Faecal calprotectin is a protein used as a diagnostic marker for inflammatory bowel diseases. We determined upper limits for normal calprotectin values for neonatal, 6, 12 and 24months old children using a turbidimetric immunoassay in a cohort of Swedish children. The advantage of the method is that opposite to previously used enzyme-linked immunosorbent assay (ELISA) method, it enables measuring single samples, and thus, shortens the analysis time significantly. There were 72 samples (41.7% female) collected neonatally, 63 samples (34.9% female) at 6months, 60 samples (40.0% female) at 12months and 51 samples (43.1% female) at 24months. The upper limits for normal values were 233, 615, 136 and 57 mu g mg(-1) for infants aged 0, 6, 12 and 24months, respectively.
KW - Calprotectin
KW - turbidimetric immunoassay
KW - normal values
KW - inflammatory bowel disease
KW - abdominal pain
KW - Calprotectin
KW - turbidimetric immunoassay
KW - normal values
KW - inflammatory bowel disease
KW - abdominal pain
UR - https://res.slu.se/id/publ/94066
U2 - 10.1080/00365513.2017.1420216
DO - 10.1080/00365513.2017.1420216
M3 - Journal article
C2 - 29283308
SN - 0036-5513
VL - 78
SP - 120
EP - 124
JO - Scandinavian Journal of Clinical and Laboratory Investigation
JF - Scandinavian Journal of Clinical and Laboratory Investigation
IS - 1-2
ER -