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Modelling ECT effects by connectivity changes in cortical neural networks

    Publication: Contribution to journal › Journal article › peer-review

    Abstract

    Biomathematical methods were applied to investigate how cortical neurodynamics depends on network connectivity. In particular, we study changes in the EEG pattern of depressed patients, following electroconvulsive therapy (ECT). The aim is to gain a better understanding of the neural mechanisms responsible for these changes, which include clear phase shifts in the EEG dynamics. This understanding is intended to provide clinical guidance in predicting ECT dose and response in depressed patients
    Original languageEnglish
    Pages (from-to)1341-1347
    Number of pages7
    JournalNeurocomputing
    Volume69
    DOIs
    Publication statusPublished - 2006

    Keywords

    • EEG
    • Clinical data
    • Neurodynamics
    • Neo-cortical network
    • Fitzhugh–Nagumo neurons

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