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Mimicking silk spinning in a microchip

  • Björn Renberg
  • , Helene Andersson-Svahn
  • , My Hedhammar

    Publication: Contribution to journal › Journal article › peer-review

    Abstract

    Nature's high performance material, spider silk, is formed during the passage of a protein solution through a spinning duct. Herein we present a microfluidic device with dual laminar mobile phases where silk formation can be mimicked and investigated. Recombinant miniature spidroins, with or without the pH-switching N-terminal domain, were used to investigate spinning conditions into silk-like fibers using this setup. (C) 2014 Elsevier B.V. All rights reserved.
    Original languageEnglish
    Pages (from-to)404-408
    Number of pages5
    JournalSensors and Actuators B: Chemical
    Volume195
    DOIs
    Publication statusPublished - 2014

    Keywords

    • Spider silk
    • Microfluidics
    • Spinning

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