How Much hydration is necessary for the stabilisation of DNA-duplex?

T.V. Maltseva; Peter Agback; J. Chattopadhyaya

doi:10.1093/nar/21.18.4246

How Much hydration is necessary for the stabilisation of DNA-duplex?

T.V. Maltseva
, Peter Agback
, J. Chattopadhyaya

Publication: Contribution to journal › Journal article › peer-review

Abstract

A combination of NOESY and ROESY experiments show that the higher stabilities (T(m)) of phenazine tethered matched (2) and G-A mismatched (4) DNA duplexes are due to the decrease of the exchange-rate (i.e. increase of the life-time) of the imino-protons and the reduced water activity in their minor grooves compared to their non-tethered counterparts (1) and (3).

Original language	English
Pages (from-to)	4246-4252
Number of pages	7
Journal	Nucleic Acids Research
Volume	21
Issue number	18
DOIs	https://doi.org/10.1093/nar/21.18.4246
Publication status	Published - 1993
Externally published	Yes

Access to Document

10.1093/nar/21.18.4246

Cite this

@article{b738e5ce5f434e5f93f81f82f4ec65e5,

title = "How Much hydration is necessary for the stabilisation of DNA-duplex?",

abstract = "A combination of NOESY and ROESY experiments show that the higher stabilities (T(m)) of phenazine tethered matched (2) and G-A mismatched (4) DNA duplexes are due to the decrease of the exchange-rate (i.e. increase of the life-time) of the imino-protons and the reduced water activity in their minor grooves compared to their non-tethered counterparts (1) and (3).",

author = "T.V. Maltseva and Peter Agback and J. Chattopadhyaya",

year = "1993",

doi = "10.1093/nar/21.18.4246",

language = "English",

volume = "21",

pages = "4246--4252",

journal = "Nucleic Acids Research",

issn = "0305-1048",