Family 7 cellobiohydrolases from Phanerochaete chrysosporium: Crystal structure of the catalytic module of Cel7D (CBH58) at 1.32 angstrom resolution and homology models of the isozymes

Ines G. Munoz; Wimal Ubhayasekera; Hongbin Henriksson; Istvan Szabo; Gunnar Johansson; Sherry Mowbray; Jerry Ståhlberg

doi:10.1006/jmbi.2000.5180

Family 7 cellobiohydrolases from Phanerochaete chrysosporium: Crystal structure of the catalytic module of Cel7D (CBH58) at 1.32 angstrom resolution and homology models of the isozymes

Ines G. Munoz
, Wimal Ubhayasekera
, Hongbin Henriksson
, Istvan Szabo
, Gunnar Johansson
, Sherry Mowbray
, Jerry Ståhlberg

Publication: Contribution to journal › Journal article › peer-review

Abstract

The Cel7D structure was used to model the products of the five other family 7 genes found in P. chrysosporium. The results suggest that at least two of these will have differences in specificity and possibly catalytic mechanism, thus offering some explanation for the presence of Cel7 isozymes in this species, which are differentially expressed in response to various growth conditions. (C) 2001 Academic Press.

Original language	English
Pages (from-to)	1097-1111
Number of pages	15
Journal	Journal of Molecular Biology
Volume	314
Issue number	5
DOIs	https://doi.org/10.1006/jmbi.2000.5180
Publication status	Published - 2001

Keywords

cellulase
cellulose
glycoside hydrolase
endoglucanase
Trichoderma reesei
homology modeling

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10.1006/jmbi.2000.5180

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Munoz, I. G., Ubhayasekera, W., Henriksson, H., Szabo, I., Johansson, G., Mowbray, S., & Ståhlberg, J. (2001). Family 7 cellobiohydrolases from Phanerochaete chrysosporium: Crystal structure of the catalytic module of Cel7D (CBH58) at 1.32 angstrom resolution and homology models of the isozymes. Journal of Molecular Biology, 314(5), 1097-1111. https://doi.org/10.1006/jmbi.2000.5180

@article{b0822e98459242adb070a7d98fe1b0e3,

title = "Family 7 cellobiohydrolases from Phanerochaete chrysosporium: Crystal structure of the catalytic module of Cel7D (CBH58) at 1.32 angstrom resolution and homology models of the isozymes",

abstract = "The Cel7D structure was used to model the products of the five other family 7 genes found in P. chrysosporium. The results suggest that at least two of these will have differences in specificity and possibly catalytic mechanism, thus offering some explanation for the presence of Cel7 isozymes in this species, which are differentially expressed in response to various growth conditions. (C) 2001 Academic Press.",

keywords = "cellulase, cellulose, glycoside hydrolase, endoglucanase, Trichoderma reesei, homology modeling, cellulase, cellulose, glycoside hydrolase, endoglucanase, Trichoderma reesei, homology modeling",

author = "Munoz, \{Ines G.\} and Wimal Ubhayasekera and Hongbin Henriksson and Istvan Szabo and Gunnar Johansson and Sherry Mowbray and Jerry St{\aa}hlberg",

year = "2001",

doi = "10.1006/jmbi.2000.5180",

language = "English",

volume = "314",

pages = "1097--1111",

journal = "Journal of Molecular Biology",

issn = "0022-2836",

publisher = "Academic Press",

number = "5",

}

Munoz, IG, Ubhayasekera, W, Henriksson, H, Szabo, I, Johansson, G, Mowbray, S & Ståhlberg, J 2001, 'Family 7 cellobiohydrolases from Phanerochaete chrysosporium: Crystal structure of the catalytic module of Cel7D (CBH58) at 1.32 angstrom resolution and homology models of the isozymes', Journal of Molecular Biology, vol. 314, no. 5, pp. 1097-1111. https://doi.org/10.1006/jmbi.2000.5180

Family 7 cellobiohydrolases from Phanerochaete chrysosporium: Crystal structure of the catalytic module of Cel7D (CBH58) at 1.32 angstrom resolution and homology models of the isozymes. / Munoz, Ines G.; Ubhayasekera, Wimal; Henriksson, Hongbin et al.
In: Journal of Molecular Biology, Vol. 314, No. 5, 2001, p. 1097-1111.

Publication: Contribution to journal › Journal article › peer-review

TY - JOUR

T1 - Family 7 cellobiohydrolases from Phanerochaete chrysosporium: Crystal structure of the catalytic module of Cel7D (CBH58) at 1.32 angstrom resolution and homology models of the isozymes

AU - Munoz, Ines G.

AU - Ubhayasekera, Wimal

AU - Henriksson, Hongbin

AU - Szabo, Istvan

AU - Johansson, Gunnar

AU - Mowbray, Sherry

AU - Ståhlberg, Jerry

PY - 2001

Y1 - 2001

N2 - The Cel7D structure was used to model the products of the five other family 7 genes found in P. chrysosporium. The results suggest that at least two of these will have differences in specificity and possibly catalytic mechanism, thus offering some explanation for the presence of Cel7 isozymes in this species, which are differentially expressed in response to various growth conditions. (C) 2001 Academic Press.

AB - The Cel7D structure was used to model the products of the five other family 7 genes found in P. chrysosporium. The results suggest that at least two of these will have differences in specificity and possibly catalytic mechanism, thus offering some explanation for the presence of Cel7 isozymes in this species, which are differentially expressed in response to various growth conditions. (C) 2001 Academic Press.

KW - cellulase

KW - cellulose

KW - glycoside hydrolase

KW - endoglucanase

KW - Trichoderma reesei

KW - homology modeling

KW - cellulase

KW - cellulose

KW - glycoside hydrolase

KW - endoglucanase

KW - Trichoderma reesei

KW - homology modeling

UR - https://res.slu.se/id/publ/53158

U2 - 10.1006/jmbi.2000.5180

DO - 10.1006/jmbi.2000.5180

M3 - Journal article

C2 - 11743726

SN - 0022-2836

VL - 314

SP - 1097

EP - 1111

JO - Journal of Molecular Biology

JF - Journal of Molecular Biology

IS - 5

ER -

Family 7 cellobiohydrolases from Phanerochaete chrysosporium: Crystal structure of the catalytic module of Cel7D (CBH58) at 1.32 angstrom resolution and homology models of the isozymes

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Keywords

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