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Effects of environmentally relevant sub-chronic atrazine concentrations on African clawed frog (Xenopus laevis) survival, growth and male gonad development

  • Cornelius Rimayi
  • , David Odusanya
  • , Jana Weiss
  • , Jacob de Boer
  • , Luke Chimuka
  • , Felix Mbajiorgu

Publication: Contribution to journalJournal articlepeer-review

Abstract

Sub-chronic toxicity of environmentally relevant atrazine concentrations on exposed tadpoles and adult male African clawed frogs (Xenopus laevis) was evaluated in a quality controlled laboratory for 90 days. The aim of this study was to determine the effects of atrazine on the survival, growth and gonad development of African clawed frogs. After exposure of tadpoles to atrazine concentrations of 0 (control), 0.01, 200 and 500 mu g L-1 in water, mortality rates of 0, 0, 3.3 and 70% respectively were recorded for the 90 day exposure period. Morphometry showed significantly reduced tadpole mass in the 500 mu g L-1 atrazine exposed tadpoles (p = 200 mu g L-1 adversely affect reproductive health of adult frogs and development of tadpoles sub-chronically exposed to atrazine.
Original languageEnglish
Pages (from-to)1-11
Number of pages11
JournalAquatic Toxicology
Volume199
DOIs
Publication statusPublished - 2018

Keywords

  • Atrazine
  • Atrazine metabolites
  • Xenopus laevis
  • Seminiferous tubule
  • Sertoli cells
  • Leydig cells
  • Testosterone

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