TY - GEN
T1 - Ebola virus disease and current therapeutic strategies: a review
AU - Diakou, Kalliopi Io
AU - Mitsis, Thanasis
AU - Pierouli, Katerina
AU - Papakonstantinou, Eleni
AU - Bongcam Rudloff, Erik
AU - Wayengera, Misaki
AU - Vlachakis, Dimitrios
PY - 2022
Y1 - 2022
N2 - The Ebola virus disease is a severe hemorrhagic fever that affects humans and other primates. Ebola virus, the causative agent of the disease, is transmitted to humans from wild animals and is highly contagious and aggressive with an estimated fatality rate to be around 50%. Since 1976, 11 outbreaks of Ebola virus disease have been reported in total, affecting mostly sub-Saharan Africa, while the most recent ongoing outbreak in the Democratic Republic of the Congo has more than 3000 reported cases and 72 deaths. Although an effective vaccine against Ebola virus disease has become available, no targeted treatment with proven efficacy upon infection is developed. Herein, we review the epidemiology of Ebola virus and the current situation in terms of prevention, diagnosis, and treatment of the disease.
AB - The Ebola virus disease is a severe hemorrhagic fever that affects humans and other primates. Ebola virus, the causative agent of the disease, is transmitted to humans from wild animals and is highly contagious and aggressive with an estimated fatality rate to be around 50%. Since 1976, 11 outbreaks of Ebola virus disease have been reported in total, affecting mostly sub-Saharan Africa, while the most recent ongoing outbreak in the Democratic Republic of the Congo has more than 3000 reported cases and 72 deaths. Although an effective vaccine against Ebola virus disease has become available, no targeted treatment with proven efficacy upon infection is developed. Herein, we review the epidemiology of Ebola virus and the current situation in terms of prevention, diagnosis, and treatment of the disease.
KW - Ebola virus
KW - Epidemiology
KW - Infectious disease
KW - Treatment
KW - Ebola virus
KW - Epidemiology
KW - Infectious disease
KW - Treatment
UR - https://res.slu.se/id/publ/115837
U2 - 10.1007/978-3-030-78787-5_18
DO - 10.1007/978-3-030-78787-5_18
M3 - Conference paper in proceedings
SN - 978-3-030-78786-8
T3 - Advances in Experimental Medicine and Biology
SP - 131
EP - 137
BT - GeNeDis 2020 : genetics and neurodegenerative diseases
PB - Springer
ER -