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Detection of early changes in sperm membrane integrity pre-freezing can estimate post-thaw quality of boar spermatozoa

  • Heriberto Rodriguez
  • , Anders Johannisson
  • , F Saravia
  • , FJ Peña
  • , M Wallgren

    Publication: Contribution to journalJournal articlepeer-review

    Abstract

    A recently developed triple staining (SNARF-1/YO-PRO-1/ethidium homodimer) was used to assess early changes in boar sperm membrane integrity (MI) with the results of cryopreservation procedures and to seek for correlations among MI-spermatozoa in pre-freeze semen and its freezeability. Ejaculates from five boars were evaluated in the fresh and frozen-thawed (FT) state, and its freezeability defined as % of membrane intactness, MI% (MI% = % of FT-spermatozoa with intact membranes x 100 divided by the % of prefreeze spermatozoa with intact membranes) estimated. Significant differences were found among boars for freezeability (MI%) and motility post-thaw (%). Interestingly, significant correlations were found between the percentage of YO-PRO-1-positive spermatozoa and freezeability (R = 0.440, p < 0.01), indicating this new triple staining can be used to safely disclose among ejaculates prior to freezing. (c) 2006 Elsevier B.V. All rights reserved.
    Original languageEnglish
    Pages (from-to)74-83
    Number of pages10
    JournalAnimal Reproduction Science
    Volume97
    Issue number45659
    DOIs
    Publication statusPublished - 2007

    Keywords

    • boar
    • cryopreservation
    • plasmalemma
    • YO-PRO-1
    • SNARF-1 ethidium homodimer
    • freezability

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