Association of canine hypothyroidism with a common major histocompatibility complex DLA class II allele

LJ Kennedy; S Quarmby; GM Happ; A Barnes; IK Ramsey; RM Dixon; B Catchpole; C Rusbridge; PA Graham; NS Hillbertz; C Roethel; WJ Dodds; NG Carmichael; WER Ollier; et al.

doi:10.1111/j.1399-0039.2006.00614.x

Association of canine hypothyroidism with a common major histocompatibility complex DLA class II allele

LJ Kennedy
, S Quarmby
, GM Happ
, A Barnes
, IK Ramsey
, RM Dixon
, B Catchpole
, C Rusbridge
, PA Graham
, NS Hillbertz
, C Roethel
, WJ Dodds
, NG Carmichael
, WER Ollier
, et al.

Publication: Contribution to journal › Journal article › peer-review

Abstract

Dogs exhibit a range of immune-mediated conditions including a lymphocytic thyroiditis which has many similarities to Hashimoto's thyroiditis in man. We have recently reported an association in Doberman Pinschers between canine hypothyroidism and a rare DLA class II haplotype that contains the DLA-DQA1*00101 allele. We now report a further series of 173 hypothyroid dogs in a range of breeds where a significant association with DLA-DQA1*00101 is shown.

Original language	English
Pages (from-to)	82-86
Number of pages	5
Journal	Tissue Antigens
Volume	68
Issue number	1
DOIs	https://doi.org/10.1111/j.1399-0039.2006.00614.x
Publication status	Published - 2006

Keywords

DLA
dogs
hypothyroidism
MHC

Access to Document

10.1111/j.1399-0039.2006.00614.x

Cite this

Kennedy, LJ., Quarmby, S., Happ, GM., Barnes, A., Ramsey, IK., Dixon, RM., Catchpole, B., Rusbridge, C., Graham, PA., Hillbertz, NS., Roethel, C., Dodds, WJ., Carmichael, NG., Ollier, WER., & et al. (2006). Association of canine hypothyroidism with a common major histocompatibility complex DLA class II allele. Tissue Antigens, 68(1), 82-86. https://doi.org/10.1111/j.1399-0039.2006.00614.x

@article{490b6ced551a463490e5c63d4ab4d063,

title = "Association of canine hypothyroidism with a common major histocompatibility complex DLA class II allele",

abstract = "Dogs exhibit a range of immune-mediated conditions including a lymphocytic thyroiditis which has many similarities to Hashimoto's thyroiditis in man. We have recently reported an association in Doberman Pinschers between canine hypothyroidism and a rare DLA class II haplotype that contains the DLA-DQA1*00101 allele. We now report a further series of 173 hypothyroid dogs in a range of breeds where a significant association with DLA-DQA1*00101 is shown.",

keywords = "DLA, dogs, hypothyroidism, MHC, DLA, dogs, hypothyroidism, MHC",

author = "LJ Kennedy and S Quarmby and GM Happ and A Barnes and IK Ramsey and RM Dixon and B Catchpole and C Rusbridge and PA Graham and NS Hillbertz and C Roethel and WJ Dodds and NG Carmichael and WER Ollier and \{Salmon Hillbertz\}, Nicolette and \{et al.\}",

year = "2006",

doi = "10.1111/j.1399-0039.2006.00614.x",

language = "English",

volume = "68",

pages = "82--86",

journal = "Tissue Antigens",

issn = "0001-2815",

publisher = "BLACKWELL PUBLISHING",

number = "1",

}

Kennedy, LJ, Quarmby, S, Happ, GM, Barnes, A, Ramsey, IK, Dixon, RM, Catchpole, B, Rusbridge, C, Graham, PA, Hillbertz, NS, Roethel, C, Dodds, WJ, Carmichael, NG, Ollier, WER & et al. 2006, 'Association of canine hypothyroidism with a common major histocompatibility complex DLA class II allele', Tissue Antigens, vol. 68, no. 1, pp. 82-86. https://doi.org/10.1111/j.1399-0039.2006.00614.x

TY - JOUR

T1 - Association of canine hypothyroidism with a common major histocompatibility complex DLA class II allele

AU - Kennedy, LJ

AU - Quarmby, S

AU - Happ, GM

AU - Barnes, A

AU - Ramsey, IK

AU - Dixon, RM

AU - Catchpole, B

AU - Rusbridge, C

AU - Graham, PA

AU - Hillbertz, NS

AU - Roethel, C

AU - Dodds, WJ

AU - Carmichael, NG

AU - Ollier, WER

AU - Salmon Hillbertz, Nicolette

AU - et al.

PY - 2006

Y1 - 2006

N2 - Dogs exhibit a range of immune-mediated conditions including a lymphocytic thyroiditis which has many similarities to Hashimoto's thyroiditis in man. We have recently reported an association in Doberman Pinschers between canine hypothyroidism and a rare DLA class II haplotype that contains the DLA-DQA1*00101 allele. We now report a further series of 173 hypothyroid dogs in a range of breeds where a significant association with DLA-DQA1*00101 is shown.

AB - Dogs exhibit a range of immune-mediated conditions including a lymphocytic thyroiditis which has many similarities to Hashimoto's thyroiditis in man. We have recently reported an association in Doberman Pinschers between canine hypothyroidism and a rare DLA class II haplotype that contains the DLA-DQA1*00101 allele. We now report a further series of 173 hypothyroid dogs in a range of breeds where a significant association with DLA-DQA1*00101 is shown.

KW - DLA

KW - dogs

KW - hypothyroidism

KW - MHC

KW - DLA

KW - dogs

KW - hypothyroidism

KW - MHC

UR - https://res.slu.se/id/publ/10936

U2 - 10.1111/j.1399-0039.2006.00614.x

DO - 10.1111/j.1399-0039.2006.00614.x

M3 - Journal article

C2 - 16774545

SN - 0001-2815

VL - 68

SP - 82

EP - 86

JO - Tissue Antigens

JF - Tissue Antigens

IS - 1

ER -

Association of canine hypothyroidism with a common major histocompatibility complex DLA class II allele

Abstract

Keywords

Access to Document

Other files and links

Cite this