Antifungal 3-hydroxy fatty acids from Lactobacillus plantarum MiLAB 14

Jörgen Sjögren; Jesper Magnusson; Anders Broberg; Johan Schnürer; Lennart Kenne

doi:10.1128/AEM.69.12.7554-7557.2003

Antifungal 3-hydroxy fatty acids from Lactobacillus plantarum MiLAB 14

Jörgen Sjögren
, Jesper Magnusson
, Anders Broberg
, Johan Schnürer
, Lennart Kenne

Publication: Contribution to journal › Journal article › peer-review

Abstract

We report the identification and chemical characterization of four antifungall substances, 3-(R)-hydroxydecanoic acid, 3-hydroxy-5-cis-dodecenoic acid, 3-(R)-hydroxydodecanoic acid and 3-(R)-hydroxytetradecanoic acid, from Lactobacillus plantarum MiLAB 14. The concentrations of the 3-hydroxy fatty acids in the supernatant followed the bacterial growth. Racemic mixtures of the saturated 3-hydroxy fatty acids showed antifungal activity against different molds and yeasts with MICs between 10 and 100 mug ml(-1).

Original language	English
Pages (from-to)	7554-7557
Number of pages	4
Journal	Applied and Environmental Microbiology
Volume	69
Issue number	12
DOIs	https://doi.org/10.1128/AEM.69.12.7554-7557.2003
Publication status	Published - 2003

Access to Document

10.1128/AEM.69.12.7554-7557.2003

Cite this

@article{1af2a88148f54f1797c4374a2cb3807d,

title = "Antifungal 3-hydroxy fatty acids from Lactobacillus plantarum MiLAB 14",

abstract = "We report the identification and chemical characterization of four antifungall substances, 3-(R)-hydroxydecanoic acid, 3-hydroxy-5-cis-dodecenoic acid, 3-(R)-hydroxydodecanoic acid and 3-(R)-hydroxytetradecanoic acid, from Lactobacillus plantarum MiLAB 14. The concentrations of the 3-hydroxy fatty acids in the supernatant followed the bacterial growth. Racemic mixtures of the saturated 3-hydroxy fatty acids showed antifungal activity against different molds and yeasts with MICs between 10 and 100 mug ml(-1).",

author = "J{\"o}rgen Sj{\"o}gren and Jesper Magnusson and Anders Broberg and Johan Schn{\"u}rer and Lennart Kenne",

year = "2003",

doi = "10.1128/AEM.69.12.7554-7557.2003",

language = "English",

volume = "69",

pages = "7554--7557",

journal = "Applied and Environmental Microbiology",

issn = "0099-2240",

publisher = "AMER SOC MICROBIOLOGY",

number = "12",

}

TY - JOUR

T1 - Antifungal 3-hydroxy fatty acids from Lactobacillus plantarum MiLAB 14

AU - Sjögren, Jörgen

AU - Magnusson, Jesper

AU - Broberg, Anders

AU - Schnürer, Johan

AU - Kenne, Lennart

PY - 2003

Y1 - 2003

N2 - We report the identification and chemical characterization of four antifungall substances, 3-(R)-hydroxydecanoic acid, 3-hydroxy-5-cis-dodecenoic acid, 3-(R)-hydroxydodecanoic acid and 3-(R)-hydroxytetradecanoic acid, from Lactobacillus plantarum MiLAB 14. The concentrations of the 3-hydroxy fatty acids in the supernatant followed the bacterial growth. Racemic mixtures of the saturated 3-hydroxy fatty acids showed antifungal activity against different molds and yeasts with MICs between 10 and 100 mug ml(-1).

AB - We report the identification and chemical characterization of four antifungall substances, 3-(R)-hydroxydecanoic acid, 3-hydroxy-5-cis-dodecenoic acid, 3-(R)-hydroxydodecanoic acid and 3-(R)-hydroxytetradecanoic acid, from Lactobacillus plantarum MiLAB 14. The concentrations of the 3-hydroxy fatty acids in the supernatant followed the bacterial growth. Racemic mixtures of the saturated 3-hydroxy fatty acids showed antifungal activity against different molds and yeasts with MICs between 10 and 100 mug ml(-1).

UR - https://res.slu.se/id/publ/611

U2 - 10.1128/AEM.69.12.7554-7557.2003

DO - 10.1128/AEM.69.12.7554-7557.2003

M3 - Journal article

C2 - 14660414

SN - 0099-2240

VL - 69

SP - 7554

EP - 7557

JO - Applied and Environmental Microbiology

JF - Applied and Environmental Microbiology

IS - 12

ER -

Antifungal 3-hydroxy fatty acids from Lactobacillus plantarum MiLAB 14

Abstract

Access to Document

Other files and links

Cite this