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A multivariate NIR study of skin alterations in diabetic patients as compared to control subjects

  • Paul Geladi
  • , Josefina Nyström
  • , JW Eriksson
  • , A. Nilsson
  • , F Lithner
  • , B Lindholm-Sethson

Publication: Contribution to journal › Journal article › peer-review

Abstract

A group of 15 diabetic persons with different degrees of diabetes complications, including skin changes, was studied by Fourier Transform Near Infrared (FT-NIR) spectroscopy. Skin reflectance spectra were measured with a fibre-optic probe in four locations (sites): hand, arm, leg and foot. For reference, a group of 28 healthy controls was also measured, Multivariate analysis of the NIR spectra obtained shows a high potential for classification and discrimination of the skin conditions. Valuable indications for future experiments can be observed.
Original languageEnglish
Pages (from-to)217-227
Number of pages11
JournalJournal of Near Infrared Spectroscopy
Volume8
Issue number4
DOIs
Publication statusPublished - 2000
Externally publishedYes

Keywords

  • FT-NIR
  • fibre-optic probe
  • PCA
  • PLS-DA
  • skin changes
  • diabetes

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