A family of putative transcription termination factors shared amongst metazoans and plants

Tomas Linder; Chan Bae Park; Jordi Asin-Cayuela; Mina Pellegrini; Nils-Göran Larsson; Maria Falkenberg; Tore Samuelsson; Claes M. Gustafsson

doi:10.1007/s00294-005-0022-5

A family of putative transcription termination factors shared amongst metazoans and plants

Tomas Linder
, Chan Bae Park
, Jordi Asin-Cayuela
, Mina Pellegrini
, Nils-Göran Larsson
, Maria Falkenberg
, Tore Samuelsson
, Claes M. Gustafsson

Publication: Contribution to journal › Journal article › peer-review

Abstract

The human mitochondrial transcription termination factor (mTERF) is involved in the regulation of transcription of the mitochondrial genome. Similarity searches and phylogenetic analysis demonstrate that mTERF is a member of large and complex protein family (the MTERF family) shared amongst metazoans and plants. Interestingly, we identify three novel MTERF genes in vertebrates, which all encode proteins with predicted mitochondrial localization. Members of the MTERF family have so far not been detected in fungi, supporting the notion that mitochondrial transcription regulation may have evolved separately in yeast and animal cells.

Original language	English
Pages (from-to)	265-269
Number of pages	5
Journal	Current Genetics
Volume	48
Issue number	4
DOIs	https://doi.org/10.1007/s00294-005-0022-5
Publication status	Published - 2005
Externally published	Yes

Keywords

mTERF
transcription
mitochondrion
termination

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10.1007/s00294-005-0022-5

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title = "A family of putative transcription termination factors shared amongst metazoans and plants",

abstract = "The human mitochondrial transcription termination factor (mTERF) is involved in the regulation of transcription of the mitochondrial genome. Similarity searches and phylogenetic analysis demonstrate that mTERF is a member of large and complex protein family (the MTERF family) shared amongst metazoans and plants. Interestingly, we identify three novel MTERF genes in vertebrates, which all encode proteins with predicted mitochondrial localization. Members of the MTERF family have so far not been detected in fungi, supporting the notion that mitochondrial transcription regulation may have evolved separately in yeast and animal cells.",

keywords = "mTERF, transcription, mitochondrion, termination, mTERF, transcription, mitochondrion, termination",

author = "Tomas Linder and Park, \{Chan Bae\} and Jordi Asin-Cayuela and Mina Pellegrini and Nils-G{\"o}ran Larsson and Maria Falkenberg and Tore Samuelsson and Gustafsson, \{Claes M.\}",

year = "2005",

doi = "10.1007/s00294-005-0022-5",

language = "English",

volume = "48",

pages = "265--269",

journal = "Current Genetics",

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T1 - A family of putative transcription termination factors shared amongst metazoans and plants

AU - Linder, Tomas

AU - Park, Chan Bae

AU - Asin-Cayuela, Jordi

AU - Pellegrini, Mina

AU - Larsson, Nils-Göran

AU - Falkenberg, Maria

AU - Samuelsson, Tore

AU - Gustafsson, Claes M.

PY - 2005

Y1 - 2005

N2 - The human mitochondrial transcription termination factor (mTERF) is involved in the regulation of transcription of the mitochondrial genome. Similarity searches and phylogenetic analysis demonstrate that mTERF is a member of large and complex protein family (the MTERF family) shared amongst metazoans and plants. Interestingly, we identify three novel MTERF genes in vertebrates, which all encode proteins with predicted mitochondrial localization. Members of the MTERF family have so far not been detected in fungi, supporting the notion that mitochondrial transcription regulation may have evolved separately in yeast and animal cells.

AB - The human mitochondrial transcription termination factor (mTERF) is involved in the regulation of transcription of the mitochondrial genome. Similarity searches and phylogenetic analysis demonstrate that mTERF is a member of large and complex protein family (the MTERF family) shared amongst metazoans and plants. Interestingly, we identify three novel MTERF genes in vertebrates, which all encode proteins with predicted mitochondrial localization. Members of the MTERF family have so far not been detected in fungi, supporting the notion that mitochondrial transcription regulation may have evolved separately in yeast and animal cells.

KW - mTERF

KW - transcription

KW - mitochondrion

KW - termination

KW - mTERF

KW - transcription

KW - mitochondrion

KW - termination

UR - https://res.slu.se/id/publ/90880

U2 - 10.1007/s00294-005-0022-5

DO - 10.1007/s00294-005-0022-5

M3 - Journal article

C2 - 16193327

SN - 0172-8083

VL - 48

SP - 265

EP - 269

JO - Current Genetics

JF - Current Genetics

IS - 4

ER -

A family of putative transcription termination factors shared amongst metazoans and plants

Abstract

Keywords

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